Recently got an update from the application team that they are unable to install and software. When executing the setup file they are getting an error pop-up window stating “Could not access VBscript run time for custom action.”. This issue was fixed using below steps:

1. Open Registry Editor” and locate the below key.

HKEY_Local_Machine\SOFTWARE\Classes\CLSID\{B54F3741-5B07-11CF-A4B0-00AA004A55E8}

2. Expand {B54F3741-5B07-11CF-A4B0-00AA004A55E8} key, locate InprocServer32 and click on it.
In the right column you should see two values.

3. Right-click InprocServer32 > Permissions > Advanced > Permissions > highlight Administrators, choose Edit > and in the Permissions check box next to Full Control; Save all changes;

4. Then in the right column or Registry Editor right-click (Default) > Modify, and insert the correct path in Value Data:

C:/Windows/system32/vbscript.dll

5. If you have 64-bit Windows repeat steps 3 – 5 for next registry keys:

HKEY_Local_Machine\SOFTWARE\Classes\Wow6432Node\CLSID\{B54F3741-5B07-11CF-A4B0-00AA004A55E8}

HKEY_Local_Machine\SOFTWARE\Wow6432Node\Classes\CLSID\{B54F3741-5B07-11CF-A4B0-00AA004A55E8

6. After that close Registry Editor.

After the above changes when we tried executing the same setup it went success.

Thanks,
WintelAdmin